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1

Infection with Human Immunodeficiency Virus Type 1 Upregulates DNA Methyltransferase, Resulting in De Novo Methylation of the Gamma Interferon (IFN-γ) Promoter and Subsequent Downregulation of IFN-γ Production

Mikovits, Judy A., Young, Howard A., Vertino, Paula, Issa, Jean-Pierre J., Pitha, Paula M., Turcoski-Corrales, Susan, Taub, Dennis D., Petrow, Cari L., Baylin, Stephen B., Ruscetti, Francis W.

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 1.46 MB

english, 1998

2

Innate Antiviral Response: Role in HIV-1 Infection

Pitha, Paula M.

Journal:

Year:

2011

Language:

english

File:

PDF, 327 KB

english, 2011

3

Preparation and properties of poly-9-vinyladenine

Paula M. Pitha, Josef Pitha

Journal:

Year:

1970

Language:

english

File:

PDF, 700 KB

english, 1970

4

Interferon treatment of murine meth-a sarcoma cells: Effects on the malignant phenotype and expression of tumor-specific and H-2 antigens

Nelson A. Wivel, Paula M. Pitha

Journal:

International Journal of Cancer

Year:

1982

Language:

english

File:

PDF, 639 KB

english, 1982

5

Viral probe into the events of cellular (in vitro) aging

Josef Pitha, Robert Adams, Paula M. Pitha

Journal:

Journal of Cellular Physiology

Year:

1974

Language:

english

File:

PDF, 572 KB

english, 1974

6

The role of cell membrane in the antiviral effect of interferon

Paula M. Pitha, Vitolis E. Vengris, Fred H. Reynolds Jr.

Journal:

Journal of Cellular Biochemistry

Year:

1976

Language:

english

File:

PDF, 340 KB

english, 1976

7

The errors in assembly of MuLV in interferon treated cells

Paula M. Pitha, Bruce Fernie, Frank Maldarelli, Nelson A. Wivel

Journal:

Journal of Cellular Biochemistry

Year:

1979

Language:

english

File:

PDF, 777 KB

english, 1979

8

Identification and genetic mapping of differentially expressed genes in mice differing at theIf1interferon regulatory locus

Christine A. Kozak, Yeu Su, N. Babu K. Raj, Paula M. Pitha

Journal:

Mammalian Genome

Year:

1999

Language:

english

File:

PDF, 139 KB

english, 1999

9

Interferon action revisited

Pitha, Paula M.

Journal:

Year:

1977

File:

PDF, 162 KB

1977

10

Expression of human β-interferon cDNA under the control of a thymidine kinase promoter from herpes simplex virus

Reyes, Gregory R., Gavis, Elizabeth R., Buchan, Alexander, Raj, N. Babu K., Hayward, Gary S., Pitha, Paula M.

Journal:

Year:

1982

File:

PDF, 541 KB

1982

11

Microsatellite instability in primary neoplasms from HIV+ patients

Bedi, Gauri C., Westra, William H., Farzadegan, Homayoon, Pitha, Paula M., Sidransky, David

Journal:

Nature Medicine

Year:

1995

File:

PDF, 352 KB

1995

12

Retinoic acid resistance in NB4 APL cells is associated with lack of interferon α synthesis Stat1 and p48 induction

Pelicano, Luis, Brumpt, Caren, Pitha, Paula M, Chelbi-Alix, Mounira K

Journal:

Year:

1999

Language:

english

File:

PDF, 534 KB

english, 1999

13

[Current Topics in Microbiology and Immunology] Interferon: The 50th Anniversary Volume 316 || The Interferon-Stimulated Genes: Targets of Direct Signaling by Interferons, Double-Stranded RNA, and Viruses

Pitha, Paula M.

Year:

2007

Language:

english

File:

PDF, 181 KB

english, 2007

14

Triggering the Interferon Response: The Role of IRF-3 Transcription Factor

Pitha, Paula, Genin, Pierre, Nguyen, Hannah, Heylbroeck, Christophe, Mamane, Yael, Algarte, Michele, Lin, Rongtuan, Hiscott, John

Journal:

Journal of Interferon & Cytokine Research

Year:

1999

Language:

english

File:

PDF, 1.12 MB

english, 1999

15

Introduction; interferons’ connection to cancer

Journal:

Seminars in Cancer Biology

Year:

2000

Language:

english

File:

PDF, 43 KB

english, 2000

16

Interferon α-Mediated Inhibition of Human Immunodeficiency Virus Type 1 Provirus Synthesis in T-Cells

Yasaman Shirazi, Paula M. Pitha

Journal:

Year:

1993

File:

PDF, 779 KB

1993

17

Differential Effect of Tumor Necrosis Factor-α and Herpes Simplex Virus Type 1 on the Tat-Targeted Inhibition of Human Immunodeficiency Virus Type 1 Replication

Waldemar Popik, Paula M. Pitha

Journal:

Year:

1994

File:

PDF, 659 KB

1994

18

Differential Regulation of the HIV-1 LTR by Specific NF-κB Subunits in HSV-1-Infected Cells

Susan L. Schafer, John Hiscott, Paula M. Pitha

Journal:

Year:

1996

Language:

english

File:

PDF, 377 KB

english, 1996

19

Early Activation of Mitogen-Activated Protein Kinase Kinase, Extracellular Signal-Regulated Kinase, p38 Mitogen-Activated Protein Kinase, and c-JunN-Terminal Kinase in Response to Binding of Simian Immunodeficiency Virus to Jurkat T Cells Expressing CCR5 Receptor

Waldemar Popik, Paula M. Pitha

Journal:

Year:

1998

Language:

english

File:

PDF, 1.70 MB

english, 1998

20

Type I Interferon Is a Powerful Inhibitor of in Vivo HIV-1 Infection and Preserves Human CD4+ T Cells from Virus-Induced Depletion in SCID Mice Transplanted with Human Cells

Caterina Lapenta, Stefano M. Santini, Enrico Proietti, Paola Rizza, Mariantonia Logozzi, Massimo Spada, Stefania Parlato, Stefano Fais, Paula M. Pitha, Filippo Belardelli

Journal:

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

21

Exploitation of Cellular Signaling by HIV-1: Unwelcome Guests with Master Keys That Signal Their Entry

Waldemar Popik, Paula M. Pitha

Journal:

Year:

2000

Language:

english

File:

PDF, 305 KB

english, 2000

22

Expression of Human and Macaque Type I IFN Transgenes Interferes with HSV-1 Replication at the Transcriptional and Translational Levels: IFN-β Is More Potent Than IFN-α2

Peter Härle, Evelyne Lauret, Paula M. Pitha, Edward De Maeyer, Daniel J.J. Carr

Journal:

Year:

2001

Language:

english

File:

PDF, 476 KB

english, 2001

23

Herpes-simplex-virus-infected cells produce a protein that binds to the TAR DNA region of the human immunodeficiency virus type 1 long terminal repeat

Jaromir Vlach, Kent W. Wilcox, Paula M. Pitha

Journal:

Journal of Biomedical Science

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

24

Retrovirus vector-targeted inducible expression of human β-interferon gene to B-cells

John F Engelhardt, Merrill J Kellum, Fatina Bisat, Paula M Pitha

Journal:

Year:

1990

Language:

english

File:

PDF, 2.73 MB

english, 1990

25

Activation of human immunodeficiency virus type 1 provirus in T-cells and macrophages is associated with induction of inducer-specific NF-κB binding proteins

Jaromir Vlach, Paula M. Pitha

Journal:

Year:

1992

Language:

english

File:

PDF, 5.91 MB

english, 1992

26

Transcriptional activation of the tat-defective human immunodeficiency virus type-1 provirus: Effect of interferon

Waldemar Popik, Paula M. Pitha

Journal:

Year:

1992

Language:

english

File:

PDF, 3.02 MB

english, 1992

27

IKKα negatively regulates IRF-5 function in a MyD88–TRAF6 pathway

Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, Paula M. Pitha

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 2.58 MB

english, 2010

28

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

Atsushi Okumura, Tim Alce, Barbora Lubyova, Heather Ezelle, Klaus Strebel, Paula M. Pitha

Journal:

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

29

Correlation between the Induction of Mouse Interferon and the Amount of Its mRNA

N. Babu Kishan RAJ, Bruce F. FERNIE, Paula M. PITHA

Journal:

Year:

1979

Language:

english

File:

PDF, 682 KB

english, 1979

30

Induction of interferon alpha genes expression

Paula M. Pitha, Wei-Chun Au*

Journal:

Seminars in Virology

Year:

1995

Language:

english

File:

PDF, 149 KB

english, 1995

31

Introduction: Interferon and interferon inducers

Journal:

Seminars in Virology

Year:

1995

Language:

english

File:

PDF, 34 KB

english, 1995

32

Poly(1-vinyluracil): The preparation and interactions with adenosine derivatives

Josef Pitha, Paula M. Pitha, Paul O.P. Ts'o

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1970

Language:

english

File:

PDF, 606 KB

english, 1970

33

119 Characterization of Murine IRF-5 and its Role in the Innate Antiviral Response

Andrea Paun, Jorgen Thomas Reinert, Paula M. Pitha

Journal:

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

34

5 The role of IRF-5 in the antiviral and inflammatory response

Mumtaz Y. Balkhi, Katherine A. Fitzgerald, Paula M. Pitha

Journal:

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

35

Employing the method of RNA interference to study the function of Kaposi’s sarcoma-associated herpesvirus-encoded vIRF-3

Barbora Lubyova, Jose A. Frisancho, Paula M. Pitha

Journal:

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

36

PS2-51 Interferon regulatory factor 5 (IRF-5) modulates the cross talk between innate and adaptive immune responses to pathogen infection

Chee-Mun Fang, Hubert Lee, Simona Stager, Paula M. Pitha

Journal:

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

37

PS2-42 Protein encoded by an isoform of IRF5 associated with autoimmune diseases is a strong transcriptional activator of the inflammatory cytokine genes

Sujayita Roy, Paula M. Pitha

Journal:

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

38

Viral defense, carcinogenesis and ISG15: Novel roles for an old ISG

Ian F. Pitha-Rowe, Paula M. Pitha

Journal:

Cytokine & Growth Factor Reviews

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007

39

Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth

Paula M. Pitha, Wei-C. Au, William Lowther, Yuang-T. Juang, Susan L. Schafer, Ladislaw Burysek, John Hiscott, Paul A. Moore

Journal:

Year:

1998

Language:

english

File:

PDF, 1.14 MB

english, 1998

40

Interferons and cytokines on a grand scale

Fran Balkwill, Paula M Pitha

Journal:

Cytokine & Growth Factor Reviews

Year:

1997

Language:

english

File:

PDF, 553 KB

english, 1997

41

The growing family of interferon regulatory factors

Hannah Nguyen, John Hiscott, Paula M. Pitha

Journal:

Cytokine & Growth Factor Reviews

Year:

1997

Language:

english

File:

PDF, 2.01 MB

english, 1997

42

Multiple effects of interferon on the replication of human immunodeficiency virus type 1

Journal:

Antiviral Research

Year:

1994

Language:

english

File:

PDF, 1.02 MB

english, 1994

43

Polynucleotide analogs as inhibitors of DNA and RNA polymerases

Paula M. Pitha, Josef Pitha

Journal:

Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors

Year:

1978

Language:

english

File:

PDF, 1.21 MB

english, 1978

44

THE EFFECTS OF INTERFERON IN MOUSE CELLS INFECTED WITH MuLV

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 1.77 MB

english, 1980

45

Effect of concanavalin A on interferon induction by poly IC

Harry D. Harper, Paula M. Pitha

Journal:

Biochemical and Biophysical Research Communications

Year:

1973

Language:

english

File:

PDF, 379 KB

english, 1973

46

Inactivation of interferon: The effect of protonation

Lewis W. Marshall, Paula M. Pitha, William A. Carter

Journal:

Year:

1972

Language:

english

File:

PDF, 495 KB

english, 1972

47

The DEAE dextran: Polyriboinosinate-polyribocytidylate complex: Physical properties and interferon induction

Paula M Pitha, William A Carter

Journal:

Year:

1971

Language:

english

File:

PDF, 418 KB

english, 1971

48

Dependence of interferon induction on cell membrane integrity

Paula M. Pitha, Harry D. Harper, Josef Pitha

Journal:

Year:

1974

Language:

english

File:

PDF, 1019 KB

english, 1974

49

Effect of interferon on exogenous, endogenous, and chronic murine leukemia virus infection

Paula M. Pitha, Wallace P. Rowe, Michael N. Oxman

Journal:

Year:

1976

Language:

english

File:

PDF, 1.27 MB

english, 1976

50

The induction of interferon and its messenger RNA in human fibroblasts

Fred H. Reynolds Jr., Paula M. Pitha

Journal:

Biochemical and Biophysical Research Communications

Year:

1974

Language:

english

File:

PDF, 371 KB

english, 1974